Urgent warning issued over common blood pressure drug linked to 12 deaths

The drug is used to treat high blood pressure, migraines, and anxiety disorders – and medics are worried

Woman with a pill.

File photo of a woman holding a pill (Image: Getty)

Medics have issued an urgent warning over a beta blocker used to treat high blood pressure and anxiety disorders.

Pharmacists and doctors have teamed up to call on regulators to review the safety advice for propranolol, a beta blocker prescribed by the NHS to treat generalised anxiety disorder, migraines, and high blood pressure.

The drug has been linked to a dozen deaths in 2023 alone, reports The Sun. The 12 people who lost their lives that year were among the 318 patients who took intentional overdoses.

That prompted the Royal College of Pharmacy (RCPharm), the Royal College of Physicians (RCP), and the National Poisons Information Service to sound the alarm over the safety advice given to patients when propranolol is prescribed for anxiety.

“While propranolol remains an effective treatment for many patients, its use for anxiety presents challenges,” said RCPharm’s medication safety officer, Kate Ryan. “We are concerned about the serious consequences of overdose, particularly for vulnerable individuals.”

NHS Nurse Holding Pills

The drug is prescribed commonly on the NHS (Image: Getty)

Dr Zuzanna Sawicka, from the RCP, added: “We are asking the Medicines and Healthcare products Regulatory Agency (MHRA) to review whether the current indication for generalised anxiety disorder and associated safety information remain appropriate.

“Strengthening awareness of these risks among healthcare professionals and patients could support safer prescribing decisions and help prevent avoidable harm.”

The letter was sent to the MHRA in July, but RCPharm only went public with its concerns last week. Responding to the letter, the MHRA said it will launch a review of propranolol harms, usage for anxiety and whether stronger safety warnings are needed, The Pharmaceutical Journal reported.

Propranolol usage has exploded in recent years, with prescriptions for teenage girls rising by 92 percent in the last decade, meaning more than a million 12-17 year-olds take it regularly, according to data reported by The Observer.

That’s despite RCPharm claiming there is ‘no proven evidence that propranolol is effective in the treatment of generalised anxiety disorder’

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